Expanding Research Horizons

I knew that I wanted to do research over the summer, but  I had to choose between research in Watershed and applying to a new project.  Watershed has been a very valuable experience to me, but I felt that I wanted to try something new.  I also felt that I should find out if I enjoy Biochemistry, since it is my major. Watershed has helped me obtain a level of comfort in the lab, which has prepared me for Chemistry and Biology lab work.  The program focuses on biological and chemical analyses of microbial communities in the Macatawa Watershed. Because of its interdisciplinary nature, I gained experience in several chemical analyses as well as biological/E. coli testing.   This required me to adapt quickly to different ways of thinking and learning.  I knew next to nothing about microbiology, or how to perform all the chemical/biological testing required for Watershed, but I learned.

My adaptability was further tested when I had the opportunity to research for Dr. Leah Chase. Her research focuses primarily on Biochemistry and Neuroscience, something I knew very little about.  Therefore, researching in this lab required some adjustment. At first, I could hardly understand my own lab partner. Additionally, the project was much more microcosmic in scope than the Watershed program. The project myresearch focuses on, system xc, an antiporter composed of two proteins that moves glutamate out of the cell and cysteine into the cell.  The system is particularly abundant in glial cells, which are essential to the function of the central nervous system.  The biochemical pathway we are studying involves the enzyme AKT, which activates a transporter called xCT.  Abnormalities in this transporter’s activity have been connected to stroke, glioma, schizophrenia, drug addiction/withdrawal, Parkinson’s disease, and Alzheimer’s disease.

Choosing a project outside of Day1 allowed me to expand my horizons past what Watershed could offer me and helped me discover that I really do love Biochemistry! I’m still thankful to the Watershed program; While I didn’t want to devote my life to it, the program  broadened my view of research and helped me discover my real passion for research. I think it is always a good idea to try new things, and joining the Chase lab has allowed me to find my passion for Biochemistry.

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